A Living Interactive Systematic Review and Meta-Analysis on Systemic Treatment Options in Metastatic Castration Resistant Prostate Cancer
The search strategy has been developed in consultation with an information specialist. The strategy is used to generate “auto” searches every month (from Medline, Embase and Cochrane Central Register of Controlled Trials [CENTRAL]). The numbers in the flowsheet are dynamically updated as new studies are considered for inclusion. Users can click the colored boxes for additional details.
How to use this flowsheet? Video demonstration
The interactive table summarizes study characteristics, population characteristics and results from the clinical trials included in this systematic review and meta-analysis. This table is dynamically updated as new studies are included in the living review. Users can select filter options to view only studies with certain characteristics or interactively construct the results table from the available menu.
How to use this table? Video demonstration
Result Table Findings.
Results are summarized as forest plots for primary analysis, sensitivity analysis, and subgroup pairwise meta-analysis. Users can select comparisons of interest using the filters provided below and can choose to view results for their outcome of interest.
The Summary of Findings (SoF) table is designed to summarize the key results of pairwise meta-analysis and to evaluate confidence in the estimates of effect. This table summarizes results for patient-important outcomes for all treatment options investigated in included trials as compared to control, in mCRPC. Users can select their outcome of interest from the left-hand panel by clicking on it and enter any baseline risk for that outcome, to visualize the absolute risk differences due to treatment